So how does Theresa May respond? With a press conference which roughly translates as "damn the torpedoes, full steam ahead!" combined with "I'm right and everyone else is wrong", at the same time as yet more Tory members are submitting letters of no confidence to the party chair (current rumours are that the magic number of 48 letters has probably been reached, with a formal announcement early next week if so).
Labour's not much better - they had a member of the shadow cabinet on the radio this morning explaining how the upcoming Tory implosion would give them an opportunity to win a general election. Because clearly gaining seats in the Commons is much more important than trying to salvage this mess.
Still, it made for good fodder for The Last Leg tonight - one of the messages they read out was "#isitok that we are only five Brexit Secretaries from Christmas?"